Questions and aswers
1. WHAT IS CAMELYN BIO?
CAMELYN BIO is the drug containing biologically active substances, including exogenous peptides isolated from mountain honey by technology of polyacrylamide gel electrophoresis. CAMELYN BIO capsules are used to harmonize immune homeostasis in order to effectively and timely counteract cancer and chronic infectious pathology.
2. WHICH ACTIVE SUBSTANCES ARE INCLUDED IN THE COMPOSITION OF CAMELYN BIO?
CAMELYN BIO is a preparation containing biologically active substances, including exogenous peptides isolated from mountain honey. Obtained from polyacrylamide gel electrophoresis, MHP-mountain honey peptides, have a complex protein structure and consist of several molecular segments: the central segment of the CP (central/core peptide) of the molecule stabilizes two peripheral peptide chains: active AP (active peptide) and binding BP (binding peptide). The central peptide provides an opportunity for peripheral conduction of active peptide-peptide interactions: activating or binding other protein molecules. The molecular weight of MHP is on average 65-75 kDa.
3. WHAT IS THE MECHANISM OF ACTION OF CAMELYN BIO?
Exogenous peptides MHP (mountain honey peptides – peptides of mountain honey), as representatives of one of the most evolutionarily ancient families of proteins, entering the body, enter into complex and diverse peptide-peptide interactions with human regulatory proteins. Camelyn Bio, due to the evolutionary properties of peptides to react with cell membrane receptors and other regulatory molecules, is able to dismember tumor cells and infected cells, recapture them to destroy T-lymphocytes, assisting macrophages to eliminate toxic pathogens, prevent metastases, and prevent relapses. Camelyn Bio improves treatment results of infectious-inflammatory processes.
4. CAMELYN BIO – IS IMMUNODUDATOR?
Camelyn Bio is not an immunomodulator. Camelyn Bio acts as a marker of atypical and infected cells, and also provides the most productive interaction of immune cells with pathogens, promotes their destruction and safely neutralizes the effects.
5. IF CAMELYN BIO IS NOT A IMMUNODUDATOR, HOW TO UNDERSTAND ITS INFLUENCE ON IMMUNITY?
The human immune system is the most difficult and at the same time the most effective system during fight with danger. Camelyn Bio, due to evolutionary ability of peptides to regulate biochemical processes, adjusts immunity to maximize effective work. Camelyn Bio creates conditions for a complete and timely immune response: masks tumors, activates lymphocytes and macrophages, assists macrophages that utilize the remains of pathogens.
6. HOW TO USE CAMELYN BIO?
Course of use of CAMELYN BIO lasts 20 days. Ampoules: 1 ampoule 2 times per day, morning and evening. For a perfect harmonization of immune homeostasis, depending on the severity of the course and stage of the disease, it is necessary to carry out from 1 to 4 or more courses of drug’s use. After using ampoules is recommended use of capsules in capacity of step therapy.
7. HOW ACTS CAMELYN BIO, IF PATIENT HAS ONCOLOGICAL DISEASES?
Developing by means of surrounding tissues, cancer cells make maximum to survive and keep their receptors intact, that is, inactive. Exogenous Camelyn Bio peptides can bind to intact cancer cell receptors and mask it. T-lymphocytes are able to identify a dangerous cell and begin work on its destruction, as well as “licensed” macrophages to capture and evacuate toxic residues.
Exogenous peptides, due to effect of tissue accumulation, (TAE-tissue accumulation effect), can mask the maximum amount of cancer cells, surround tumor hems and prevent metastases. Due to ETN, exogenous peptides create additional obstacles to the formation of invasive centers for circulating tumor cells and metastatic embolisms.
Moreover, due to its evolutionarily programmed ability to react with other protein structures, Camelyn Bio exogenous peptides join tumor cell membranes and thus provoke their more productive interactions with T lymphocytes, NK cells and macrophages. Macrophages synthesize TNF and even more macrophages and T-cells are licensed to fight tumors, the intensity of expression of antitumor interleukin-12 increases. This, in turn, leads to increased immune tumor surveillance, prevents recurrence and prevents metastases.
8. I HAVE CHRONIC PROSTATY. WHY URGOLOGY RECOMMENDS ME CAMELYN BIO WHICH IS APPLICABLE FOR TREATMENT OF CANCER?
Yes, the drug is recommended for patients with cancer. But also, CAMELYN BIO is used in the schemes of complex therapy of infectious and inflammatory processes. The effect of tissue accumulation of exogenous peptides is the key to understanding mechanisms for the harmonization of immune homeostasis in patients with chronic bacterial prostatitis. In urological practice, Camelyn Bio causes a more pronounced positive dynamics in the growth of the immunoregulatory index, as well as a relatively higher increase in the number of activated T-lymphocytes. This leads to significant better results of the integrated treatment of infectious-inflammatory processes of the prostate.
9. HOW DOES CAMELYN BIO INFLUENCE ON THE IMMUNITY?
The process of activation or recruiting of lymphocytes is difficult and carries a whole cascade of interactions of extracellular, membrane and intracellular structures. Studies have shown that in order for lymphocyte to react to an infection, its internal receptors should receive protein signals from pathogens: viruses or bacteria. In this process, the causal role is played by catelcidine. It activates the pores through which bacterial fragments enter the lymphocyte and activate the NLR (NOD-like receptors).
In conditions of chronic infection or in the development of cancer, that is, in conditions of chronic immunodeficiency, there is a violation of peptide-peptide interactions in the body. Regulatory protein LL-37 often remains inactive, the cell calcification time does not pass the fragments of pathogens and NOD-like receptors of lymphocytes do not receive signals from bacteria and viruses. Many lymphocytes remain inactive, the cascade of immune responses is not triggered in full volume.
Exogenous peptides of CAMELYN BIO, as representatives of one of the most evolutionarily ancient families of proteins, entering the body, enter into complex and diverse peptide-peptide interactions with human regulatory proteins. For example, having a similar molecular weight with catelcidine, MHP is capable of acting as its activator and, therefore, induces inactive T-lymphocytes to effectively counteract pathogens.
10. WHAT IS THE MECHANISM OF ACTION OF CAMELYN BIO ON VIRAL HEPATITIS?
In conditions of chronic liver cells (hepatocytes), the significance of a specific protein – glypin-3 – is determined. With alcoholic liver disease, at toxic and viral hepatitis, the role of this peptide on cell membranes is recognized as a determining factor in the development of the disease. And the higher the activity of glypican, the greater possibility of malignancy (malignant transformation) of the liver cells.
Glypican-3 has central and peripheral peptide chains (HS). To trigger the process of malignancy and further proliferation of cancer cells, the glypican, using the peripheral proteinaceous HS-chains, should be connected to the HGF protein.
Due to effect of tissue accumulation, exogenous Camelyn Bio peptides, in contact with liver cell membranes, block the HS-chains of glypican-3 and hinder their interaction with HGF. As a result, the risk of malignancy of hepatocytes and complication of hepatitis with liver cancer is reduced. And in the case of a diagnosis of hepatocellular carcinoma – the progress of the disease is stopped, quality and life expectancy is improved.
11. HOW DOES CAMELYN BIO DEMONSTRATE DETOXICATION PROPERTIES?
Under the influence of chemotherapy, the tumor tissue collapses, saturating the body with toxic fragments. The tissues of the tumor are disintegrating, fragmenting, dying. This is the strongest stress for the body, life-threatening intoxication. Protein fragments of destroyed cancer cells need to be recognized and disposed of, with which they are called to handle macrophages.
It should be noted that the main problem for purifying the body from the remains of destroyed cells – is primarily their various spatial sizes and molecular mass. It is also important that each fragment has its antigenic structure, making it difficult for macrophages to recognize and utilize.
Camelyn Bio peptides with the help of peripheral peptide chains bind to residues of destroyed cells, toxic protein fragments and stabilize them. Connected with the MNR, protein residues acquire large amounts and their molecular weight at the expense of the Camelyn Bio peptides reaches 22-30 or more kDa. The increased size of the fragments allows the macrophages to find the target quickly.
Stabilized fragments of molecules are easier to absorb, but most importantly, all Camelyn-Bio stabilized by peptides fragments have the same signal area, which allows licensed macrophages not only to capture them more quickly and efficiently, but also to transmit information on the immune cascade to the largest number of immune cells.
12. I HAVE CERVICAL DYSPLASIA. WHY DOES THE GYNECOLOGY RECOMMEND ME CAMELYN BIO WHICH IS APPLICABLE FOR TREATMENT OF CANCER?
processes. Camelyn Bio is effective in dysplasia of the cervix of the uterus of I, II phase, which is caused by a mixed chlamydial-papillomaviral infection. Adequate complex therapy, taking into account the role of exogenous peptides, helps to reduce the activity of the human papillomavirus (HPV), its elimination, which reduces the frequency of relapses. Camelyn Bio provides increased concentration of secretory immunoglobulin A (sIgA) in the mucus of the cervical canal, as well as contributes to the normalization of expression of CD3 and CD4 lymphocytes, stimulates the synthesis of interleukins 1? And 18.
13. I HAVE ADDITIONAL QUESTIONS. CAN I RECEIVE CONSULTATION?
Yes of course. We are ready to provide exhaustive answers to all your questions.